Recombinant human ADH1A protein

ADH1A, also known as alcohol dehydrogenase 1A, belongs to the alcohol dehydrogenase family. It plays a key role in hepatic alcohol catabolism. Its activity may be the cause of disorders in metabolic pathways that use these isoenzymes and could increase the concentration of acetaldehyde, which is cancerogenic substance. It is positively correlated with those of CDR1, CDR2 and FLU1. Recombinant human ADH1A, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Alcohol dehydrogenase 1A, ADH1A, ADH1

Expression System

Baculovirus

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 95% by SDS-PAGE

Molecular Weight

40.6 kDa (381aa)

Additionnal Information

ADH1A, Alcohol dehydrogenase 1A, ADH1A, ADH1, ATGP3480-10 µg, ATGP3480-20 µg, ATGP3480-50 µg, ATGP3480-100 µg, ATGP3480-250 µg, ATGP3480-500 µg, ATGP3480-1 mg, ATGP3480-10, ATGP3480-20, ATGP3480-50, ATGP3480-100, ATGP3480-250, ATGP3480-500, ATGP3480-1

References & Citations

Orywal K., et al. (2010) J Clin Lab Anal. 24:334-339.; ; Yasunami M., et al. (1990) Genomics. 7:152-158.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Signal Transduction

NCBI Accession Number

NP_000658

Uniprot Accession Number

P07327

Species

Human

N Terminal Sequence

Met1

AA Sequence

MSTAGKVIKC KAAVLWELKK PFSIEEVEVA PPKAHEVRIK MVAVGICGTD DHVVSGTMVT PLPVILGHEA AGIVESVGEG VTTVKPGDKV IPLAIPQCGK CRICKNPESN YCLKNDVSNP QGTLQDGTSR FTCRRKPIHH FLGISTFSQY TVVDENAVAK IDAASPLEKV CLIGCGFSTG YGSAVNVAKV TPGSTCAVFG LGGVGLSAIM GCKAAGAARI IAVDINKDKF AKAKELGATE CINPQDYKKP IQEVLKEMTD GGVDFSFEVI GRLDTMMASL LCCHEACGTS VIVGVPPDSQ NLSMNPMLLL TGRTWKGAIL GGFKSKECVP KLVADFMAKK FSLDALITHV LPFEKINEGF DLLHSGKSIR TILMFHHHHH H