Recombinant human ULBP-1 protein
ULBP1, also known as NKG2D ligand 1, is a member of a family of cell-surface proteins that function as ligands for human NKG2D. It is unconventional MHC class I-like molecules exploited by viruses and cancer. Its ligand Methylation contributes to immune system evasion in acute myeloid leukemia. It is independent predictors of good prognosis in cervical cancer. Recombinant human ULBP1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Specifications
Human ULBP-1 is coated at 10 µg/mL (100 ul/well) can bind NKG2D (CAT# ATGP3662) in a Functional ELISA assay.
Product Name Alternative
UL16 binding protein 1, ALCAN-beta, NKG2D ligand 1, N2DL-1, NKG2DL1, Retinoic acid early transcript 1I, RAET1I
Expression System
Baculovirus
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Bioactivity
Concentration
0.5 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 90% by SDS-PAGE
Bioactivity
Measured by its binding ability in a functional ELISA with Human NKG2D (CAT# ATGP3662) .
Molecular Weight
23.4 kDa (200aa)
Additionnal Information
References & Citations
Baragano Raneros A., et al. (2015) Genes Immun. 16:71-82.; ; Cerwenka A., et al. (2003) Tissue Antigens. 61:335-343.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Immunology
NCBI Accession Number
NP_079494
Uniprot Accession Number
Q9BZM6
Species
Human
N Terminal Sequence
Ala
AA Sequence
Frequently Asked Questions
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