Recombinant human MFAP4 protein

MFAP4, also as known as microfibrillar-associated protein 4, belongs to Fibrinogen protein family and contains 1 fibrinogen C-terminal domain. This protein has similarity to a bovine microfibril-associated protein. The protein has binding specificities for both collagen and carbohydrate. It is thought to be an extracellular matrix protein which is involved in cell adhesion or intercellular interactions. Deletion of MFAP4 was found in 30 of 31 patients with Smith-Magenis syndrome (SMS), a clinically recognizable multiple congenital anomaly/mental retardation syndrome. Recombinant human MFAP4, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Microfibril-associated glycoprotein 4 isoform 2, MFAP4

Expression System

Baculovirus

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

27.5 kDa (243aa)

Additionnal Information

MFAP4, Microfibril-associated glycoprotein 4 isoform 2, MFAP4, ATGP3476-10 µg, ATGP3476-20 µg, ATGP3476-50 µg, ATGP3476-100 µg, ATGP3476-250 µg, ATGP3476-500 µg, ATGP3476-1 mg, ATGP3476-10, ATGP3476-20, ATGP3476-50, ATGP3476-100, ATGP3476-250, ATGP3476-500, ATGP3476-1

References & Citations

Lausen M. et al., (1999) J Biol Chem. 274:32234-32240.; ; Zhao Z. et al., (1995) Mol. Genet. 4: 589-597.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Signal Transduction

NCBI Accession Number

NP_002395

Uniprot Accession Number

P55083

Species

Human

N Terminal Sequence

Ala

AA Sequence

VSGIRGD ALERFCLQQP LDCDDIYAQG YQSDGVYLIY PSGPSVPVPV FCDMTTEGGK WTVFQKRFNG SVSFFRGWND YKLGFGRADG EYWLGLQNMH LLTLKQKYEL RVDLEDFENN TAYAKYADFS ISPNAVSAEE DGYTLFVAGF EDGGAGDSLS YHSGQKFSTF DRDQDLFVQN CAALSSGAFW FRSCHFANLN GFYLGGSHLS YANGINWAQW KGFYYSLKRT EMKIRRA