Recombinant mouse Rae-1 epsilon protein
Raet1e, also known as retinoic acid early-inducible protein 1-epsilon, is a member of a family of cell-surface proteins that function as ligands for mouse NKG2D. All Rae-1 family members bind to mouse NKG2D, an activating receptor expressed on NK cells and some T cell subsets, resulting in the activation of cytolytic activity and cytokine production by these effector cells. Recombinant mouse Raet1e, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Retinoic acid early-inducible protein 1-epsilon, Raet1e
Expression System
Baculovirus
Antigen Species
Mouse
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 95% by SDS-PAGE
Molecular Weight
23.5 kDa (207aa)
Additionnal Information
References & Citations
Diefenbach A., et al. (2000) Nat Immunol. 1:119-126.; ; Cerwenka A., et al. (2001) Proc Natl Acad Sci USA. 98:11521-11526.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Immunology
NCBI Accession Number
NP_937836
Uniprot Accession Number
Q9CZQ6
Species
Mouse
N Terminal Sequence
Leu29
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