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Recombinant human CD66a/CEACAM1 protein

CEACAM1, also known as carcinoembryonic antigen-related cell adhesion molecule 1 isoform 6, is a member of the carcinoembryonic antigen (CEA) gene family which belongs to the immunoglobulin superfamily. This protein is a surface glycoprotein expressed on various blood cells, epithelial cells, and vascular cells. It performs actions in multiple cellular processes including tissue differentiation, angiogenesis, apoptosis, metastasis, as well as the modulation of innate and adaptive immune responses. Recombinant human CEACAM1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Carcinoembryonic antigen-related cell adhesion molecule 1 isoform 6, CEACAM1, BGP, BGP1, BGPI, CEA cell adhesion molecule 1, Biliary glycoprotein 1

Expression System

Baculovirus

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

44.6 kDa (405aa)

Additionnal Information

CEACAM1, CD66a, ATGP3441-10 µg, ATGP3441-20 µg, ATGP3441-50 µg, ATGP3441-100 µg, ATGP3441-250 µg, ATGP3441-500 µg, ATGP3441-1 mg, ATGP3441-10, ATGP3441-20, ATGP3441-50, ATGP3441-100, ATGP3441-250, ATGP3441-500, ATGP3441-1

References & Citations

Beauchemin N., et al. (1999) Exp. Cell Res. 252:243-349.; ; Bogoevska V., et al. (2006) Glycobiology. 16:197-209.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Cancer

NCBI Accession Number

NP_001192273

Uniprot Accession Number

P13688

Species

Human

N Terminal Sequence

Ala

AA Sequence

QLTTE SMPFNVAEGK EVLLLVHNLP QQLFGYSWYK GERVDGNRQI VGYAIGTQQA TPGPANSGRE TIYPNASLLI QNVTQNDTGF YTLQVIKSDL VNEEATGQFH VYPELPKPSI SSNNSNPVED KDAVAFTCEP ETQDTTYLWW INNQSLPVSP RLQLSNGNRT LTLLSVTRND TGPYECEIQN PVSANRSDPV TLNVTYGPDT PTISPSDTYY RPGANLSLSC YAASNPPAQY SWLINGTFQQ STQELFIPNI TVNNSGSYTC HANNSVTGCN RTTVKTIIVT ELSPVVAKPQ IKASKTTVTG DKDSVNLTCS TNDTGISIRW FFKNQSLPSS ERMKLSQGNT TLSINPVKRE DAGTYWCEVF NPISKNQSDP IMLNVNYNAL PQENGLSPG
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