Recombinant human MMP-1 protein
MMP1, also known as interstitial collagenase isoform 1, contains 4 hemopexin-like domains and is a member of the matrix metalloproteinase (MMP) family. It is capable of degrading a wide range of extracellular molecules and a number of bioactive molecules. It plays a central role in cell proliferation, migration, differentiation, angiogenesis, apoptosis and host defences. Recombinant human MMP1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Interstitial collagenase isoform 1, MMP1, CLG, CLGN
Expression System
Baculovirus
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 95% by SDS-PAGE
Molecular Weight
53.1 kDa (460aa)
Additionnal Information
References & Citations
Kumar JD., et al. (2015) Am J Physiol Gastrointest Liver Physiol. 309:G78-G86.; ; Yang H., et al. (2015) Biochemistry. 54:3631-3639.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM MES buffer (pH 5.5) containing 10 mM CaCl2, 100 mM NaCl, 0.05% Brij35, 30% glycerol
Scientific Category
Adhesion & Movement
NCBI Accession Number
NP_002412
Uniprot Accession Number
P03956
Species
Human
N Terminal Sequence
His18
AA Sequence
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