Recombinant human CLEC-2/CLEC1B protein
CLEC1B, as known as C-type lectin domain family 1 member B, is a type 2 transmembrane glycoprotein and member of the C-type lectin-like family of receptors. This protein is expressed preferentially in liver, and is also detected in myeloid cells, platelets, and megakaryocytes. It has been reported that CLEC2/CLEC1B meditates powerful platelet aggregation by binding to the snake venom protein, rhodocytin and the molecule podoplanin. Recombinant human CLEC1B, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
C-type lectin domain family 1 member B, CLEC2, CLEC-2
Expression System
Baculovirus
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 90% by SDS-PAGE
Molecular Weight
21.8 kDa (184aa)
Additionnal Information
References & Citations
Chaipan C., et al, (2006) J. Virol. 80:8951-8960.; ; Colonna M., et al, (2000) Eur. J. Immunol. 30:697-704.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Immunology
NCBI Accession Number
NP_057593
Uniprot Accession Number
Q9P126
Species
Human
N Terminal Sequence
Ala
AA Sequence
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