Recombinant human IL-23R protein

IL23R, also known as interleukin-23 receptor, belongs to the type I cytokine receptor family, Type 2 subfamily. It contains 2 fibronectin type-III domains and is expressed by monocytes, Th1, Th0, NK and dendritic cells. It may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis. Recombinant human IL23R, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Interleukin-23 receptor, IL-23R, IL-23 receptor

Expression System

Baculovirus

Antigen Species

Human

Tag

HIgG-His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

65.3 kDa (574aa)

Additionnal Information

Interleukin-23 receptor, Interleukin23 receptor, Interleukin 23 receptor, IL23R_HUMAN, IL-23R, IL23R, IL-23 receptor, IL23 receptor, IL-23 R, IL23 R, IL 23R, IL 23 receptor, ATGP3424-10 µg, ATGP3424-20 µg, ATGP3424-50 µg, ATGP3424-100 µg, ATGP3424-250 µg, ATGP3424-500 µg, ATGP3424-1 mg, ATGP3424-010, ATGP3424-020, ATGP3424-050, ATGP3424-100, ATGP3424-250, ATGP3424-500, ATGP3424-01M

References & Citations

Dubinsky MC., et al. (2007) Inflamm Bowel Dis. 13:511-515.; ; Yao J., et al. (2014) Gene. 533:21-25.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Immunology

NCBI Accession Number

NP_653302.2

Uniprot Accession Number

Q5VWK5

Species

Human

N Terminal Sequence

Ala

AA Sequence

GITNINC SGHIWVEPAT IFKMGMNISI YCQAAIKNCQ PRKLHFYKNG IKERFQITRI NKTTARLWYK NFLEPHASMY CTAECPKHFQ ETLICGKDIS SGYPPDIPDE VTCVIYEYSG NMTCTWNAGK LTYIDTKYVV HVKSLETEEE QQYLTSSYIN ISTDSLQGGK KYLVWVQAAN ALGMEESKQL QIHLDDIVIP SAAVISRAET INATVPKTII YWDSQTTIEK VSCEMRYKAT TNQTWNVKEF DTNFTYVQQS EFYLEPNIKY VFQVRCQETG KRYWQPWSSL FFHKTPETVP QVTSKAFQHD TWNSGLTVAS ISTGHLTSDN RGDIG