Recombinant human IL-4 protein

IL4, also known as Interleukin 4 isoform1, is a pleiotropic cytokine that has many biological roles, including the stimulation of activated B-cell and T-cell proliferation, and the differentiation of naive helper T-cell to Th2 cells. IL4 is a co-stimulator of DNA-synthesis and is induces the expression of class II MHC molecules on resting B-cells. It also enhances both secretion and cell surface expression of IgE and IgG1. Recombinant human IL4, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Specifications

Human IL-4 stimulates cell proliferation of the TF-1 human erythroleukemic cells. The ED50 range ≤0.6 ng/mL.

Product Name Alternative

Pitrakinra, MGC79402, Lymphocyte stimulatory factor 1, Interleukin-4 isoform 1, Interleukin 4, IL-4, BSF1, Binetrakin, BCGF1, B-cell stimulatory factor 1, B-cell growth factor 1, BCDF

Expression System

E.coli

Antigen Species

Human

Tag

Non-Tagged

Applications

SDS-PAGE, Bioactivity

Concentration

1 mg/mL (determined by BCA assay)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 95% by SDS-PAGE

Bioactivity

Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 range ≤0.6 ng/mL.

Molecular Weight

15 kDa (130aa)

Additionnal Information

Pitrakinra, Pitrakinara, MGC79402, Lymphocyte stimulatory factor 1, Interleukin-4 isoform 1, Interleukin-4, Interleukin4, Interleukin 4 isoform 1, Interleukin 4, IL-4, IL4, IL 4, BSF-1, BSF1, BSF 1, Binetrakin, BCGF-1, BCGF1, BCGF 1, B-cell stimulatory factor 1, B-cell growth factor 1, BCDF, B cell stimulatory factor 1, B cell growth factor 1, ATGP3421-10 µg, ATGP3421-20 µg, ATGP3421-50 µg, ATGP3421-100 µg, ATGP3421-250 µg, ATGP3421-500 µg, ATGP3421-1 mg, ATGP3421-010, ATGP3421-020, ATGP3421-050, ATGP3421-100, ATGP3421-250, ATGP3421-500, ATGP3421-01M