Recombinant human IL-29/IFNL1 protein
IFNL1, as known as interferon lambda-1, is a secreted protein which belongs to the IL28/29 family. It is a cytokine with immunomodulatory activity. This protein is highly similar in amino acid sequence to the IL28. Also, it plays an important role in host defenses against microbes and its gene is highly upregulated in cells infected with viruses. It may play a role in antiviral immunity. Recombinant human IFNL1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Interferon lambda 1, IFN-lambda-1, Cytokine Zcyto21, ZCYTO21, Interleukin-29, IL-29
Expression System
Baculovirus
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 90% by SDS-PAGE
Molecular Weight
20.8 kDa (187aa)
Additionnal Information
References & Citations
Meager A., et al. (2005) Cytokine 31:109-118.; ; Dumoutier L., et al. (2004) J. Biol. Chem. 279:32269-32274.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Immunology
NCBI Accession Number
NP_742152
Uniprot Accession Number
Q8IU54
Species
Human
N Terminal Sequence
Gly20
AA Sequence
Frequently Asked Questions
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