Recombinant human IL-29/IFNL1 protein

IFNL1, as known as interferon lambda-1, is a secreted protein which belongs to the IL28/29 family. It is a cytokine with immunomodulatory activity. This protein is highly similar in amino acid sequence to the IL28. Also, it plays an important role in host defenses against microbes and its gene is highly upregulated in cells infected with viruses. It may play a role in antiviral immunity. Recombinant human IFNL1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Interferon lambda 1, IFN-lambda-1, Cytokine Zcyto21, ZCYTO21, Interleukin-29, IL-29

Expression System

Baculovirus

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

20.8 kDa (187aa)

Additionnal Information

IL29, IFN-lambda1, Interferon lambda-1, IFNL1, IL-29, IL29, Cytokine ZCYTO21, IFN lambda 1, IFN-lambda-1, IL29_HUMAN, Interferon lambda 1, Interferon lambda-1, Interleukin 29 (interferon, lambda 1), Interleukin-29, ATGP3419-10 µg, ATGP3419-20 µg, ATGP3419-50 µg, ATGP3419-100 µg, ATGP3419-250 µg, ATGP3419-500 µg, ATGP3419-1 mg, ATGP3419-10, ATGP3419-20, ATGP3419-50, ATGP3419-100, ATGP3419-250, ATGP3419-500, ATGP3419-1

References & Citations

Meager A., et al. (2005) Cytokine 31:109-118.; ; Dumoutier L., et al. (2004) J. Biol. Chem. 279:32269-32274.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Immunology

NCBI Accession Number

NP_742152

Uniprot Accession Number

Q8IU54

Species

Human

N Terminal Sequence

Gly20

AA Sequence

GPVPTSKPTT TGKGCHIGRF KSLSPQELAS FKKARDALEE SLKLKNWSCS SPVFPGNWDL RLLQVRERPV ALEAELALTL KVLEAAAGPA LEDVLDQPLH TLHHILSQLQ ACIQPQPTAG PRPRGRLHHW LHRLQEAPKK ESAGCLEASV TFNLFRLLTR DLKYVADGNL CLRTSTHPES THHHHHH