Recombinant human RLBP1 protein

RLBP1, as known as retinaldehyde binding protein 1, is a soluble protein. It participates in the regeneration of active 11-cis-retinol and 11-cis-retinaldehyde, from the inactive 11-trans products of the rhodopsin photocycle and in the de novo synthesis of these retinoids from 11-trans metabolic precursors. The cycling of retinoids between photoreceptor and adjacent pigment epithelium cells is known as the 'visual cycle'. Recombinant human RLBP1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Retinaldehyde binding protein 1, RLBP1, CRALBP, Cellular retinaldehyde binding protein like, CRALBPL, FLJ37248, Retinaldehyde binding protein 1 like 1, RLBP1L1

Expression System

Baculovirus

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

37.5 kDa (326aa)

Additionnal Information

RLBP1, Retinaldehyde binding protein 1 , RLBP1, CRALBP, Cellular retinaldehyde binding protein like, CRALBPL, FLJ37248, Retinaldehyde binding protein 1 like 1, RLBP1L1, ATGP3410-10 µg, ATGP3410-20 µg, ATGP3410-50 µg, ATGP3410-100 µg, ATGP3410-250 µg, ATGP3410-500 µg, ATGP3410-1 mg, ATGP3410-10, ATGP3410-20, ATGP3410-50, ATGP3410-100, ATGP3410-250, ATGP3410-500, ATGP3410-1

References & Citations

Neutzner RV., et al. (2011) Ophthalmologe 108:1045-1049.; ; Intres R., et al. (1994) J. Biol. Chem. 269:25411-25418.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 20% glycerol

Scientific Category

Neuroscience

NCBI Accession Number

NP_000317.1

Uniprot Accession Number

P12271

Species

Human

N Terminal Sequence

Ala

AA Sequence

MSEGVGT FRMVPEEEQE LRAQLEQLTT KDHGPVFGPC SQLPRHTLQK AKDELNEREE TREEAVRELQ EMVQAQAASG EELAVAVAER VQEKDSGFFL RFIRARKFNV GRAYELLRGY VNFRLQYPEL FDSLSPEAVR CTIEAGYPGV LSSRDKYGRV VMLFNIENWQ SQEITFDEIL QAYCFILEKL LENEETQING FCIIENFKGF TMQQAASLRT SDLRKMVDML QDSFPARFKA IHFIHQPWYF TTTYNVVKPF LKSKLLERVF VHGDDLSGFY QEIDENILPS DFGGTLPKYD GKAVAEQLFG PQAQAENTAF