Recombinant human RLBP1 protein
RLBP1, as known as retinaldehyde binding protein 1, is a soluble protein. It participates in the regeneration of active 11-cis-retinol and 11-cis-retinaldehyde, from the inactive 11-trans products of the rhodopsin photocycle and in the de novo synthesis of these retinoids from 11-trans metabolic precursors. The cycling of retinoids between photoreceptor and adjacent pigment epithelium cells is known as the 'visual cycle'. Recombinant human RLBP1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Expression System
Baculovirus
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 90% by SDS-PAGE
Molecular Weight
37.5 kDa (326aa)
Additionnal Information
References & Citations
Neutzner RV., et al. (2011) Ophthalmologe 108:1045-1049.; ; Intres R., et al. (1994) J. Biol. Chem. 269:25411-25418.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 20% glycerol
Scientific Category
Neuroscience
NCBI Accession Number
NP_000317.1
Uniprot Accession Number
P12271
Species
Human
N Terminal Sequence
Ala
AA Sequence
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
