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Recombinant mouse Carnosine Dipeptidase 1/CNDP1 protein

Cndp1, as known as beta-Ala-His dipeptidase, is a member of the M20 metalloprotease family. In human, this protein is secreted from the liver into the serum. In other mammals, including rodents, it is expressed exclusively within the kidney and lacks a signal peptide. Also, it is a secreted homodimeric dipeptidase that specifically hydrolyzes L-carnosine, and is identified as human carnosinase expressed in the brain. Recombinant mouse Cndp1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Beta-Ala-His dipeptidase, CNDP dipeptidase 1, Carnosine dipeptidase 1, CN1, Carnosinase 1

Expression System

Baculovirus

Antigen Species

Mouse

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 95% by SDS-PAGE

Molecular Weight

56.1 kDa (500aa)

Additionnal Information

AI746433, Beta Ala His dipeptidase, Beta-Ala-His dipeptidase, Carnosinase 1, Carnosinase1, Carnosine dipeptidase 1, Carnosine dipeptidase1, CN 1, CN1, CN-1, CNDP 1, CNDP dipeptidase 1, CNDP dipeptidase1, CNDP1, CNDP-1, ATGP3408-10 µg, ATGP3408-20 µg, ATGP3408-50 µg, ATGP3408-100 µg, ATGP3408-250 µg, ATGP3408-500 µg, ATGP3408-1 mg, ATGP3408-010, ATGP3408-020, ATGP3408-050, ATGP3408-100, ATGP3408-250, ATGP3408-500, ATGP3408-01M

References & Citations

Janssen B., et al, (2005) Diabetes. 54:2320-2327.; ; Teufel M., et al, (2003) J. Biol. Chem. 278:6521-6531.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Signal Transduction

NCBI Accession Number

NP_803233

Uniprot Accession Number

Q8BUG2

Species

Mouse

N Terminal Sequence

Met1

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