Recombinant mouse EphA4 protein
Epha4, as known as ephrin type-A receptor 4, is a single-pass type 1 membrane protein which belongs to the protein kinase superfamily and ephrin receptor subfamily. This protein may play a role in a signal transduction process involved in hindbrain pattern formation. The ephrins and ephrin receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Recombinant mouse Epha4, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques
Product Specifications
Product Name Alternative
EPH receptor A4, Ephrin type-A receptor 4, Tyrosine-protein kinase receptor MPK-3, Tyrosine-protein kinase receptor SEK-1, Cek8, Hek8, rb, Sek, Tyro1
Expression System
Baculovirus
Antigen Species
Mouse
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 95% by SDS-PAGE
Molecular Weight
59.3 kDa (536aa)
Additionnal Information
References & Citations
Borgius L., et al. (2014) J. Neurosci. 34:3841-3853.; ; Steinecke A., et al. (2014) Development 141:460-471.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Cardiovascular
NCBI Accession Number
NP_031962
Uniprot Accession Number
Q03137
Species
Mouse
N Terminal Sequence
Val20
AA Sequence
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