Recombinant human Kallikrein 2/KLK2 protein

KLK2, also known as kallikerin-2 isoform1, is a secreted serine protease that is highly expressed in the human prostate gland. The enzyme is highly specific for cleavage after arginine residues. This protein is able to activate the urokinase-type plasminogen activator. It is inhibited by serpins such as protein C inhibitor, antichymotrypsin and plasminogen activator inhibitor. Recombinant human KLK2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Kallikrein related peptidase 2, Glandular kallikrein-1, hGK-1, Tissue kallikrein-2, Prostatic kallikrein 2

Expression System

Baculovirus

Antigen Species

Human, Canine, Influenza A-H3N2 (canine), Influenza A

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

27.2 kDa (246aa)

Additionnal Information

Kallikrein2, Kallikerin-2 isoform1 , KLK2, hGK-1, hK2, KLK2A2, Glandular kallikrein 2Glandular kallikrein-1, hGK 1, hGK-1, hK2, Kallikrein 2 prostatic, Kallikrein related peptidase 2, kallikrein, glandular, Kallikrein, prostatic, Kallikrein-2, KLK 2Klk-2, Klk2, KLK2_HUMAN, KLK2A 2, KLK2A2MGC12201, Tissue kallikrein 2, Tissue kallikrein-2Ton, ATGP3399-10 µg, ATGP3399-20 µg, ATGP3399-50 µg, ATGP3399-100 µg, ATGP3399-250 µg, ATGP3399-500 µg, ATGP3399-1 mg, ATGP3399-10, ATGP3399-20, ATGP3399-50, ATGP3399-100, ATGP3399-250, ATGP3399-500, ATGP3399-1

References & Citations

Frenette G., et al. (1997) Int J Cancer. 71:897-899.; ; Mikolajczyk SD., et al. (1999) Cancer Res. 59:3927-3930.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Signal Transduction

NCBI Accession Number

NP_005542

Uniprot Accession Number

P20151

Species

Human, Canine, Influenza A-H3N2 (canine), Influenza A

N Terminal Sequence

Ala

AA Sequence

IVGGWEC EKHSQPWQVA VYSHGWAHCG GVLVHPQWVL TAAHCLKKNS QVWLGRHNLF EPEDTGQRVP VSHSFPHPLY NMSLLKHQSL RPDEDSSHDL MLLRLSEPAK ITDVVKVLGL PTQEPALGTT CYASGWGSIE PEEFLRPRSL QCVSLHLLSN DMCARAYSEK VTEFMLCAGL WTGGKDTCGG DSGGPLVCNG VLQGITSWGP EPCALPEKPA VYTKVVHYRK WIKDTIAANP