Recombinant human C1q R1/CD93 protein

CD93, also known as complement component C1q receptor, belongs to a family of transmembrane glycoproteins which also includes endosialin and thrombomodulin. It is involved in various aspects of inflammatory reactions. CD93 is expressed by vascular endothelial cells and by a variety of hematopoietic cells. It is receptor for C1q, mannose-binding lectin (MBL2) and pulmonary surfactant protein A (SPA) . Recombinant human CD93, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Complement component C1q receptor, CD93, C1qR (P), C1QR1, C1qRP, CDw93, dJ737E23.1, ECSM3, MXRA4, C1q receptor 1, C1q/MBL/SPA receptor, C1qR, C1qR (p), C1qr1, C1QR1_HUMAN, C1qRp, CD93, CD93 antigen, CD93 molecule, CDw93, Complement component 1 q subcomponent receptor 1, Complement component C1q receptor, dJ737E23.1, ECSM3, Matrix remodeling associated protein 4, Matrix remodelling associated 4, Matrix-remodeling-associated protein 4, MXRA4

Expression System

Baculovirus

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

59.3 kDa (567aa)

Additionnal Information

C1q R1, CD93, Complement component C1q receptor , CD93, C1qR (P), C1QR1, C1qRP, CDw93, dJ737E23.1, ECSM3, MXRA4, C1q receptor 1C1q/MBL/SPA receptor, C1qR, C1qR (p), C1qr1C1QR1_HUMAN, C1qRp, CD93, CD93 antigenCD93 molecule, CDw93, Complement component 1 q subcomponent receptor 1, Complement component C1q receptor, dJ737E23.1, ECSM3, Matrix remodeling associated protein 4, Matrix remodelling associated 4Matrix-remodeling-associated protein 4, MXRA4, ATGP3395-10 µg, ATGP3395-20 µg, ATGP3395-50 µg, ATGP3395-100 µg, ATGP3395-250 µg, ATGP3395-500 µg, ATGP3395-1 mg, ATGP3395-10, ATGP3395-20, ATGP3395-50, ATGP3395-100, ATGP3395-250, ATGP3395-500, ATGP3395-1

References & Citations

McGreal EP., et al. (2002) J Immunol. 168:5222-5232.; ; Chevrier S., et al. (2009) Proc Natl Acad Sci USA. 106:3895-3900.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Immunology

NCBI Accession Number

NP_036204

Uniprot Accession Number

Q9NPY3

Species

Human

N Terminal Sequence

Thr22

AA Sequence

TGADTEAVVC VGTACYTAHS GKLSAAEAQN HCNQNGGNLA TVKSKEEAQH VQRVLAQLLR REAALTARMS KFWIGLQREK GKCLDPSLPL KGFSWVGGGE DTPYSNWHKE LRNSCISKRC VSLLLDLSQP LLPSRLPKWS EGPCGSPGSP GSNIEGFVCK FSFKGMCRPL ALGGPGQVTY TTPFQTTSSS LEAVPFASAA NVACGEGDKD ETQSHYFLCK EKAPDVFDWG SSGPLCVSPK YGCNFNNGGC HQDCFEGGDG SFLCGCRPGF RLLDDLVTCA SRNPCSSSPC RGGATCVLGP HGKNYTCRCP QGYQLDSSQL DCVDVDECQD SPCAQECVNT PGGFRCECWV GYEPGGPGEG ACQDVDECAL GRSPCAQGCT NTDGSFHCSC EEGYVLAGED GTQCQDVDEC VGPGGPLCDS LCFNTQGSFH CGCLPGWVLA PNGVSCTMGP VSLGPPSGPP DEEDKGEKEG STVPRAATAS PTRGPEGTPK ATPTTSRPSL SSDAPITSAP LKMLAPSGSP GVWREPSIHH ATAASGPQEP AGGDSSVATQ NNDGTDGQKV EHHHHHH