Recombinant human ALDOC protein

ALDOC, also as known as fructose bisphosphate C, is a member of the class 1 fructose-biphosphate aldolase family. This protein is a ubiquitous enzyme that catalyzes the reversible aldol cleavage of fructose-bisphosphate and fructose 1-phospate to digydroxyacetone phosphate and either glyceral-dehyde-3-phosphate or glyceraldegyde, respectively. It is expressed specifically in the hippocampus and Purkinje cells of the brain. Recombinant human ALDOC was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Fructose bisphosphate aldolase C, ALDC, ALDC, ALDO C, aldoc, ALDOC_HUMAN, Aldolase 3, Aldolase C Fructose bisphosphate, Brain type aldolase, Brain-type aldolase, Fructoaldolase C, Fructose 1 6 biphosphate triosephosphate lyase, Fructose bisphosphate aldolase C, Fructose-bisphosphate aldolase C

Expression System

E.coli

Antigen Species

Human

Tag

Non-Tagged

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

39.4 kDa (364aa) confirmed by MALDI-TOF

Additionnal Information

ALDOC, Fructose bisphosphate aldolase C , ALDC, ALDC, ALDO C, aldoc, ALDOC_HUMAN, Aldolase 3, Aldolase C Fructose bisphosphateBrain type aldolase, Brain-type aldolaseFructoaldolase C, Fructose 1 6 biphosphate triosephosphate lyase, Fructose bisphosphate aldolase C, Fructose-bisphosphate aldolase C, ATGP3393-10 µg, ATGP3393-20 µg, ATGP3393-50 µg, ATGP3393-100 µg, ATGP3393-250 µg, ATGP3393-500 µg, ATGP3393-1 mg, ATGP3393-10, ATGP3393-20, ATGP3393-50, ATGP3393-100, ATGP3393-250, ATGP3393-500, ATGP3393-1

References & Citations

Rolland T. et al., (2014) Cell. 159 (5) :1212-26.; ; Caspi M. et al., (2014) Mol Cancer. 13:164.; ; Arakaki TL. et al., (2004) Protein Sci. 13 (12) : 3077-84

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 2mM DTT, 0.1M NaCl

Scientific Category

Cancer

NCBI Accession Number

NP_005156.1

Uniprot Accession Number

P09972

Species

Human

AA Sequence

MPHSYPALSA EQKKELSDIA LRIVAPGKGI LAADESVGSM AKRLSQIGVE NTEENRRLYR QVLFSADDRV KKCIGGVIFF HETLYQKDDN GVPFVRTIQD KGIVVGIKVD KGVVPLAGTD GETTTQGLDG LSERCAQYKK DGADFAKWRC VLKISERTPS ALAILENANV LARYASICQQ NGIVPIVEPE ILPDGDHDLK RCQYVTEKVL AAVYKALSDH HVYLEGTLLK PNMVTPGHAC PIKYTPEEIA MATVTALRRT VPPAVPGVTF LSGGQSEEEA SFNLNAINRC PLPRPWALTF SYGRALQASA LNAWRGQRDN AGAATEEFIK RAEVNGLAAQ GKYEGSGEDG GAAAQSLYIA NHAY