Recombinant human STI1/STIP1 protein

STIP1, also known as stress-induced-phosphoprotein 1 isoform b, belongs to the large group of co-chaperones. The main function of STIP1 is to link Hsp70 and Hsp90 together. STIP1 also modulates the chaperone activities of the linked proteins and possibly interacts with other chaperones and proteins. It forms a complex with HSC70 and HSPCA/HSP-86 and HSPCB/HSP-84, as well as interacting with PACRG. Recombinant human STIP1 was expressed in E. coli and purified by using conventional chromatography techniques

Product Specifications

Product Name Alternative

Stress-induced-phosphoprotein 1, Hsc70/Hsp90-organizing protein, Hop, Renal carcinoma antigen NY-REN-11, Transformation-sensitive protein IEF SSP 3521

Expression System

E.coli

Antigen Species

Human

Tag

Non-Tagged

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

62.6 kDa (543aa) confirmed by MALDI-TOF

Additionnal Information

STI1, Stress-induced-phosphoprotein 1 , STI1, HEl-S-94n, HOP, IEF-SSP-3521, P60, STI1L, Epididymis secretory sperm binding protein Li 94nHEL S 94n, HopHsc70/Hsp90 organizing protein, IEF SSP 3521NY REN 11 antigen, P60Renal carcinoma antigen NY-REN-11STI1, STI1L, STIP1, STIP1_HUMANStress induced phosphoprotein 1Transformation sensitive protein IEF SSP 3521, ATGP3391-10 µg, ATGP3391-20 µg, ATGP3391-50 µg, ATGP3391-100 µg, ATGP3391-250 µg, ATGP3391-500 µg, ATGP3391-1 mg, ATGP3391-10, ATGP3391-20, ATGP3391-50, ATGP3391-100, ATGP3391-250, ATGP3391-500, ATGP3391-1

References & Citations

Johnson BD., et al. (1998) J Biol Chem. 273 (6) :3679-86.; ; Van Der Spuy J., et al. (2001) Protein Expr Purif. 21 (3) :462-9.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT, 0.1M NaCl

Scientific Category

Heat Shock Proteins

NCBI Accession Number

NP_006810

Uniprot Accession Number

P31948

Species

Human

AA Sequence

MEQVNELKEK GNKALSVGNI DDALQCYSEA IKLDPHNHVL YSNRSAAYAK KGDYQKAYED GCKTVDLKPD WGKGYSRKAA ALEFLNRFEE AKRTYEEGLK HEANNPQLKE GLQNMEARLA ERKFMNPFNM PNLYQKLESD PRTRTLLSDP TYRELIEQLR NKPSDLGTKL QDPRIMTTLS VLLGVDLGSM DEEEEIATPP PPPPPKKETK PEPMEEDLPE NKKQALKEKE LGNDAYKKKD FDTALKHYDK AKELDPTNMT YITNQAAVYF EKGDYNKCRE LCEKAIEVGR ENREDYRQIA KAYARIGNSY FKEEKYKDAI HFYNKSLAEH RTPDVLKKCQ QAEKILKEQE RLAYINPDLA LEEKNKGNEC FQKGDYPQAM KHYTEAIKRN PKDAKLYSNR AACYTKLLEF QLALKDCEEC IQLEPTFIKG YTRKAAALEA MKDYTKAMDV YQKALDLDSS CKEAADGYQR CMMAQYNRHD SPEDVKRRAM ADPEVQQIMS DPAMRLILEQ MQKDPQALSE HLKNPVIAQK IQKLMDVGLI AIR