Recombinant human TACI/TNFRSF13B protein

TNFRSF13B, also known as tumor necrosis factor receptor superfamily member 13B, is a member of the tumor necrosis factor receptor superfamily. It is a trimeric cytokine receptor that binds tumor necrosis factors (TNF) . It cooperates with an adaptor protein which is important in determining the outcome of the response. It has crucial roles in both innate and adaptive immunity and in cellular apoptosis process. Recombinant human TNFRSF13B, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

TNF receptor superfamily member 13B, Transmembrane activator and CAML interactor, TACI, CD267, IGAD2

Expression System

Baculovirus

Antigen Species

Human

Tag

HIgG-His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

45.8 kDa (407aa)

Additionnal Information

CD 267, CD267, CD267 antigen, CVID, CVID2, FLJ39942, IGAD2, MGC133214, MGC39952, OTTHUMP00000065442, RYZN, TACI, TNF receptor superfamily member 13B, TNFRSF 13B, TNFRSF13B, TNFRSF13B protein, TR13B_HUMAN, Transmembrane activator and CAML interactor, Tumor necrosis factor receptor 13B, Tumor necrosis factor receptor superfamily member 13B, ATGP3386-10 µg, ATGP3386-20 µg, ATGP3386-50 µg, ATGP3386-100 µg, ATGP3386-250 µg, ATGP3386-500 µg, ATGP3386-1 mg, ATGP3386-010, ATGP3386-020, ATGP3386-050, ATGP3386-100, ATGP3386-250, ATGP3386-500, ATGP3386-01M

References & Citations

Salzer U., et al. (2005) Nat Genet. 37:820-828.; ; Mohammadi J., et al. (2009) J Clin Immunol. 29:777-785.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 30% glycerol, 1mM DTT

Scientific Category

Immunology

NCBI Accession Number

NP_036584

Uniprot Accession Number

O14836

Species

Human

N Terminal Sequence

Ala

AA Sequence

ADLMSGLGRS RRGGRSRVDQ EERFPQGLWT GVAMRSCPEE QYWDPLLGTC MSCKTICNHQ SQRTCAAFCR SLSCRKEQGK FYDHLLRDCI SCASICGQHP KQCAYFCENK LRSPVNLPPE LRRQRSGEVE NNSDNSGRYQ GLEHRGSEAS PALPGLKLSA DQVALVYSLE PKSCDKTHTC PPCPAPELLG GPSVFLFPPK PKDTLMISRT PEVTCVVVDV SHEDPEVKFN WYVDGVEVHN AKTKPREEQY NSTYRVVSVL TVLHQDWLNG KEYKCKVSNK ALPAPIEKTI SKAKGQPREP QVYTLPPSRD ELTKNQVSLT CLVKGFYPSD IAVEWESNGQ PENNYKTTPP VLDSDGSFFL YSKLTVDKSR WQQGNVFSCS VMHEALHNHY TQKSLSLSPG KHHHHHH