Recombinant human Pepsinogen C/PGC protein

PGC, also known as gastricsin, is an aspartic proteinase that belongs to the peptidase family A1. It is synthesized in the gastric mucosa as inactive precursors. It contains a prosegment that serves to stabilize the inactive form and prevent entry of the substrate to the active site. Serum levels of PGC are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Recombinant human PGC, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques

Product Specifications

Product Name Alternative

Gastricsin, PGC, PEPC, PGII, Gastricsin, PEPC_HUMAN, pepsin C, Pepsinogen C, pepsinogen group II, PGII, preprogastricsin, Progastricsin

Expression System

Baculovirus

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 95% by SDS-PAGE

Molecular Weight

41.6 kDa (380aa)

Additionnal Information

Pepsinogen PGC, Gastricsin, PGC, PEPC, PGII, Gastricsin, PEPC_HUMAN, pepsin C, Pepsinogen C, pepsinogen group II, PGII, preprogastricsin, Progastricsin, ATGP3385-10 µg, ATGP3385-20 µg, ATGP3385-50 µg, ATGP3385-100 µg, ATGP3385-250 µg, ATGP3385-500 µg, ATGP3385-1 mg, ATGP3385-10, ATGP3385-20, ATGP3385-50, ATGP3385-100, ATGP3385-250, ATGP3385-500, ATGP3385-1