Recombinant human DDR2 protein
DDR2, also known as discoidin domain-containing receptor 2, belongs to the discoidin-like domain containing subfamily of receptor tyrosine kinases. It is mainly expressed in mesenchymal cells and is unique amog RTKs in that its ligand is fibrillar collagen rather than a growth factor-like peptide. Recombinant human DDR2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Expression System
Baculovirus
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 90% by SDS-PAGE
Molecular Weight
43.7 kDa (386aa)
Additionnal Information
References & Citations
Vogel WF., et al. (2006) Cell. Signal. 18:1108-1116.; ; Wall SJ., et al. (2005) J Biol Chem. 48:40187-40194.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Neuroscience
NCBI Accession Number
NP_001014796.1
Uniprot Accession Number
Q16832
Species
Human
N Terminal Sequence
Lys22
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