Recombinant human a-N-acetylgalactosaminidase protein

NAGA, also known as alpha-N-acetylgalactosaminidase, is a lysosomal exoglycosidase that cleaves terminal alpha-N-acetylgalactosamine residues from glycopeptides and glycolipids. It is hardly expected to cause an allergic reaction in Fabry disease patients. It is highly promising as a new and safe enzyme for ERT for Fabry disease. Recombinant human NAGA, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Alpha-N-acetylgalactosaminidase, NAGA, D22S674, GALB, Acetylgalactosaminidase, alpha N (alpha galactosidase B), Alpha galactosidase B, Alpha N acetylgalactosaminidase, N acetylgalactosaminidase, alpha

Expression System

Baculovirus

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

45.5 kDa (400aa)

Additionnal Information

A-N-acetylgalactosaminidase, Alpha-N-acetylgalactosaminidase, NAGA, D22S674, GALB, Acetylgalactosaminidase, alpha N (alpha galactosidase B), Alpha galactosidase B, Alpha N acetylgalactosaminidase, N acetylgalactosaminidase, alpha, ATGP3377-10 µg, ATGP3377-20 µg, ATGP3377-50 µg, ATGP3377-100 µg, ATGP3377-250 µg, ATGP3377-500 µg, ATGP3377-1 mg, ATGP3377-10, ATGP3377-20, ATGP3377-50, ATGP3377-100, ATGP3377-250, ATGP3377-500, ATGP3377-1