Recombinant human CD66c/CEACAM6 protein

CEACAM6, also known as Carcinoembryonic antigen-related cell adhesion molecule 6, belongs to the human carcino-embryonic antigen (CEA) family. It is a member of glycosylphosphatidylinositol-linked immunoglobulin superfamily that is implicated in a variety of human cancers. It is associated with the progression of pancreatic cancer. Recombinant human CEACAM6, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

CEA cell adhesion molecule 6, Carcinoembryonic antigen-related cell adhesion molecule 6, Non-specific cross reacting antigen, NCA, CD66c

Expression System

Baculovirus

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 95% by SDS-PAGE

Molecular Weight

32.6 kDa (297aa)

Additionnal Information

CEACAM6, CD66c, Carcinoembryonic antigen-related cell adhesion molecule 6, CEACAM6, CD66c, CEAL, NCAm, Carcinoembryonic antigen related cell adhesion molecule 6, Carcinoembryonic antigen related cell adhesion molecule 6 (non specific cross reacting antigen), Carcinoembryonic antigen-related cell adhesion molecule 6, CD 66c, CD66c, CD66c antigen, CEA LIKE PROTEIN, CEACAM 6, CEACAM6, CEAL, CEAM6_HUMAN, MGC93832, NCA, Non specific cross reacting antigen, Non-specific crossreacting antigen, Normal cross reacting antigen, Normal cross-reacting antigen, ATGP3376-10 µg, ATGP3376-20 µg, ATGP3376-50 µg, ATGP3376-100 µg, ATGP3376-250 µg, ATGP3376-500 µg, ATGP3376-1 mg, ATGP3376-10, ATGP3376-20, ATGP3376-50, ATGP3376-100, ATGP3376-250, ATGP3376-500, ATGP3376-1

References & Citations

Yan L., et al. (2016) Oncol Rep. 35:418-426.; ; Zang M., et al. (2015) Biochim Biophys Acta. 1852:1020-1028.; ; Cheng TM., et al. (2014) Eur J Cancer. 50:713-721.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Cancer

NCBI Accession Number

NP_002474.4

Uniprot Accession Number

P40199

Species

Human

N Terminal Sequence

Ala

AA Sequence

KLTIE STPFNVAEGK EVLLLAHNLP QNRIGYSWYK GERVDGNSLI VGYVIGTQQA TPGPAYSGRE TIYPNASLLI QNVTQNDTGF YTLQVIKSDL VNEEATGQFH VYPELPKPSI SSNNSNPVED KDAVAFTCEP EVQNTTYLWW VNGQSLPVSP RLQLSNGNMT LTLLSVKRND AGSYECEIQN PASANRSDPV TLNVLYGPDV PTISPSKANY RPGENLNLSC HAASNPPAQY SWFINGTFQQ STQELFIPNI TVNNSGSYMC QAHNSATGLN RTTVTMITVS G