Recombinant mouse Endoglin/CD105 protein

Eng, also known as endoglin, is a type I homodimeric transmembrane glycoprotein with a large, disulfide-linked, extracellular region and a short, constitutively phosphorylated cytoplasmic tail. It is highly expressed on vascular endothelial cells, chondrocytes, and syncytiotrophoblasts of term placenta. It is also found on activated monocytes, mesenchymal stem cells and leukemic cells of lymphoid and myeloid lineages. Recombinant mouse Eng, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Specifications

Mouse Endoglin (CAT# ATGP3361) is coated at 10 µg/mL (100 ul/well) can bind Human TGF-beta RI (CAT# ATGP4134) in a Functional ELISA assay.

Product Name Alternative

AI528660, AI662476, CD105, Cell surface MJ7/18 antigen, Endo, Endoglin, Eng, ORW, ORW1, Osler-Rendu-Weber syndrome 1, S-endoglin

Expression System

Baculovirus

Antigen Species

Mouse

Tag

His-Tag

Applications

SDS-PAGE, Bioactivity

Concentration

0.5 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 95% by SDS-PAGE

Bioactivity

Measured by its binding ability in a functional ELISA with Human TGF-beta RI (CAT# ATGP4134) .

Molecular Weight

60.9 kDa (563aa)

Additionnal Information

AI528660, AI662476, CD 105, CD105, CD-105, Cell surface MJ7/18 antigen, Endo, Endoglin, Eng, ORW, ORW 1, ORW1, Osler Rendu Weber syndrome 1, Osler-Rendu-Weber syndrome 1, S endoglin, S-endoglin, ATGP3361-10 µg, ATGP3361-20 µg, ATGP3361-50 µg, ATGP3361-100 µg, ATGP3361-250 µg, ATGP3361-500 µg, ATGP3361-1 mg, ATGP3361-010, ATGP3361-020, ATGP3361-050, ATGP3361-100, ATGP3361-250, ATGP3361-500, ATGP3361-01M