Recombinant human Integrin beta 2/CD18 protein

ITGB2, also known as integrin beta-2, is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It may belong to an extended family of cell surface molecules including the fibronectin binding protein. Also It is a complement receptor type 3 (CR3) . It triggers neutrophil transmigration during lung injury through PTK2B/PYK2-mediated activation. Recombinant human ITGB2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

ITGB2, Cell surface adhesion glycoproteins LFA-1, CR3, p150,95 subunit beta, Complement receptor C3 subunit beta, MFI7, MAC-1

Expression System

Baculovirus

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by Bradford assay)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 85% by SDS-PAGE

Molecular Weight

75.9 kDa (686aa)

Additionnal Information

Integrin a L b2, Integrin beta-2, ITGB2, CD18, LAD, LCAMB, LFA-1, MAC-1, MF17, MFI7, ATGP3351-10 µg, ATGP3351-20 µg, ATGP3351-50 µg, ATGP3351-100 µg, ATGP3351-250 µg, ATGP3351-500 µg, ATGP3351-1 mg, ATGP3351-10, ATGP3351-20, ATGP3351-50, ATGP3351-100, ATGP3351-250, ATGP3351-500, ATGP3351-1