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Recombinant mouse OPG/TNFRSF11B protein

Tnfrsf11b, also known as tumor necrosis factor receptor superfamily member 11B, is a member of the tumor necrosis factor receptor TNFR superfamily. It inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Also It plays a role in preventing arterial calcification. Recombinant mouse Tnfrsf11B, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Tumor necrosis factor receptor superfamily member 11B, Osteoclastogenesis inhibitory factor, Osteoprotegerin, OCIF, OPG, TR1

Expression System

Baculovirus

Antigen Species

Mouse

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

44.4 kDa (388aa)

Additionnal Information

Osteoprotegerin, TNFRSF11B, Tumor necrosis factor receptor superfamily member 11B, Tnfrsf11b, OCIF, Opg, TR1, ATGP3350-10 µg, ATGP3350-20 µg, ATGP3350-50 µg, ATGP3350-100 µg, ATGP3350-250 µg, ATGP3350-500 µg, ATGP3350-1 mg, ATGP3350-10, ATGP3350-20, ATGP3350-50, ATGP3350-100, ATGP3350-250, ATGP3350-500, ATGP3350-1

References & Citations

Min H., et al. (2000) J Exp Med. 192:463-474.; ; Simonet WS., et al. (1997) Cell. 89:309-319.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Immunology

NCBI Accession Number

NP_032790

Uniprot Accession Number

O08712

Species

Mouse

N Terminal Sequence

Glu22

Curated Selection

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