Recombinant human 14-3-3 eta protein
14-3-3 eta also as known as YWHAH. This protein belong to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. 14-3-3 eta interacts with and relocalizes the A20 zinc finger protein from the insoluble to the soluble fraction, suggesting a chaperone function. It implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binding to a large number of partners, usually by recognition of a phosphothreonine motif. Recombinant Human 14-3-3 eta was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
YWHAH, YWHA1, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta, Protein AS1
Expression System
E.coli
Antigen Species
Human
Tag
Non-Tagged
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by absorbance at 280 nm)
Purity
> 90% by SDS-PAGE
Molecular Weight
28.2 kDa (246aa)
Additionnal Information
References & Citations
Maksymowych WP., et al. (2014) Arthritis Res Ther. 16 (2) : R99.; ; Sato S., et al. (2002) J Biol Chem. 277: 39360-39367
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Signal Transduction
NCBI Accession Number
NP_003396
Uniprot Accession Number
Q04917
Species
Human
AA Sequence
Frequently Asked Questions
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