Recombinant mouse IL-5R alpha/IL5RA protein
Il5ra, also known as interleukin-5 receptor subunit alpha, is known to regulate the development and function of eosinophils. This protein is a therapeutic target for hypereosinophilic diseases including allergic inflammations and asthma. Oct2 enhances antibody-secreting cell differentiation through regulation of IL-5 receptor alpha chain expression on activated B cells. Recombinant mouse Il5ra, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Interleukin-5 receptor subunit alpha, Il5ra, CD125, CDw125, Il5r, IL-5 receptor subunit alpha; IL-5R subunit alpha
Expression System
Baculovirus
Antigen Species
Mouse
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 90% by SDS-PAGE
Molecular Weight
37.8 kDa (330aa)
Additionnal Information
References & Citations
Bhattacharya M., et al. (2007) Biopolymers. 88:83-93.; ; Emslie D., et al. (2008) J Exp Med. 205:409-421.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Immunology
NCBI Accession Number
NP_032396
Uniprot Accession Number
P21183
Species
Mouse
N Terminal Sequence
Asp18
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