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Recombinant mouse IL-5R alpha/IL5RA protein

Il5ra, also known as interleukin-5 receptor subunit alpha, is known to regulate the development and function of eosinophils. This protein is a therapeutic target for hypereosinophilic diseases including allergic inflammations and asthma. Oct2 enhances antibody-secreting cell differentiation through regulation of IL-5 receptor alpha chain expression on activated B cells. Recombinant mouse Il5ra, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Interleukin-5 receptor subunit alpha, Il5ra, CD125, CDw125, Il5r, IL-5 receptor subunit alpha; IL-5R subunit alpha

Expression System

Baculovirus

Antigen Species

Mouse

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

37.8 kDa (330aa)

Additionnal Information

IL5 R a, Interleukin-5 receptor subunit alpha, Il5ra, CD125, CDw125, Il5r, ATGP3344-10 µg, ATGP3344-20 µg, ATGP3344-50 µg, ATGP3344-100 µg, ATGP3344-250 µg, ATGP3344-500 µg, ATGP3344-1 mg, ATGP3344-10, ATGP3344-20, ATGP3344-50, ATGP3344-100, ATGP3344-250, ATGP3344-500, ATGP3344-1

References & Citations

Bhattacharya M., et al. (2007) Biopolymers. 88:83-93.; ; Emslie D., et al. (2008) J Exp Med. 205:409-421.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Immunology

NCBI Accession Number

NP_032396

Uniprot Accession Number

P21183

Species

Mouse

N Terminal Sequence

Asp18

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