Recombinant human CD38 protein

CD38, also known as ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, is a surface molecule which has been attributed the function of a signaling channel leading to cellular activation and proliferation, an ectoenzyme with multiple function as well as an inducer of Ca2+ mobilization from cytoplasmic stores. It also functions as a plasma membrane signaling receptor in leukocytes. On B cells, It acts as a coreceptor and modulates B cell receptor (BCR) signals. Recombinant human CD38, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, CD38, ADPRC 1, ADPRC1

Expression System

Baculovirus

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

31.2 kDa (269aa)

Additionnal Information

CD38, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, CD38, ADPRC 1, ADPRC1, ATGP3339-10 µg, ATGP3339-20 µg, ATGP3339-50 µg, ATGP3339-100 µg, ATGP3339-250 µg, ATGP3339-500 µg, ATGP3339-1 mg, ATGP3339-10, ATGP3339-20, ATGP3339-50, ATGP3339-100, ATGP3339-250, ATGP3339-500, ATGP3339-1

References & Citations

Funaro A., et al. (1997) Tissue Antigens. 49:7-15.; ; Lischke., et al. (2013) Infect Immun. 81:4091-4099.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 50 mM MES buffer (pH 5.0) containing 100 mM NaCl, 10% glycerol

Scientific Category

Immunology

NCBI Accession Number

NP_001766

Uniprot Accession Number

P28907

Species

Human

N Terminal Sequence

Ala

AA Sequence

ADPEFVPRWR QQWSGPGTTK RFPETVLARC VKYTEIHPEM RHVDCQSVWD AFKGAFISKH PCNITEEDYQ PLMKLGTQTV PCNKILLWSR IKDLAHQFTQ VQRDMFTLED TLLGYLADDL TWCGEFNTSK INYQSCPDWR KDCSNNPVSV FWKTVSRRFA EAACDVVHVM LNGSRSKIFD KNSTFGSVEV HNLQPEKVQT LEAWVIHGGR EDSRDLCQDP TIKELESIIS KRNIQFSCKN IYRPDKFLQC VKNPEDSSCT SEIHHHHHH