Recombinant human CD38 protein
CD38, also known as ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, is a surface molecule which has been attributed the function of a signaling channel leading to cellular activation and proliferation, an ectoenzyme with multiple function as well as an inducer of Ca2+ mobilization from cytoplasmic stores. It also functions as a plasma membrane signaling receptor in leukocytes. On B cells, It acts as a coreceptor and modulates B cell receptor (BCR) signals. Recombinant human CD38, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, CD38, ADPRC 1, ADPRC1
Expression System
Baculovirus
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 90% by SDS-PAGE
Molecular Weight
31.2 kDa (269aa)
Additionnal Information
References & Citations
Funaro A., et al. (1997) Tissue Antigens. 49:7-15.; ; Lischke., et al. (2013) Infect Immun. 81:4091-4099.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 50 mM MES buffer (pH 5.0) containing 100 mM NaCl, 10% glycerol
Scientific Category
Immunology
NCBI Accession Number
NP_001766
Uniprot Accession Number
P28907
Species
Human
N Terminal Sequence
Ala
AA Sequence
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