Recombinant mouse CD55/DAF protein
CD55, also known as Complement decay-accelerating factor, GPI-anchored, is a member of the RCA (regulators of complement activation) family characterized by four to 30 SCRs (short consensus repeats) in their plasma-exposed regions. It is physiologically acting as an inhibitor of the complement system, but is also broadly expressed in malignant tumours. Recombinant mouse CD55, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Complement decay-accelerating factor, GPI-anchored, Daf, Daf-GPI, Daf1, GPI-DAF, Cd55
Expression System
Baculovirus
Antigen Species
Mouse
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 95% by SDS-PAGE
Molecular Weight
36.8 kDa (336aa)
Additionnal Information
References & Citations
Lea S., et al. (2002) Biochem Soc Trans. 30:1014-1019.; ; Wang Y., et al. (2010) J Neuroinflammation. 7:24.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Immunology
NCBI Accession Number
NP_034146
Uniprot Accession Number
Q61475
Species
Mouse
N Terminal Sequence
Asp35
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