Recombinant human TNFR1/TNFRSF1A protein

TNFRSF1A, also known as tumor necrosis factor receptor superfamily member 1A, is a member of CD family, tumor necrosis factor receptor superfamily. It is one of the most primary receptors for the tumor necrosis factor-alpha. It has been shown to be localized to both plasma membrane lipid rafts and the trans golgi complex with the help of the death domain. Recombinant human TNFRSF1A, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Tumor necrosis factor receptor superfamily member 1A, Tumor necrosis factor receptor 1, TNF-R1, Tumor necrosis factor receptor type I, TNF-RI, TNFR-I, Tumor necrosis factor-binding protein 1, TBPI, CS120a, p55, p60, TNF-R55, TNFR60

Expression System

Baculovirus

Antigen Species

Human

Tag

HIgG-His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

47.7 kDa (424aa)

Additionnal Information

TNF RI, TNFRSF1A, Tumor necrosis factor receptor superfamily member 1A, CD120a, FPF, MS5, p55, p55-R, p60, TBP1, TNF-R, TNF-R-I, TNF-R55, TNFAR, TNFR1, TNFR1-d2, TNFR55, TNFR60, TNFRSF1A, ATGP3326-10 µg, ATGP3326-20 µg, ATGP3326-50 µg, ATGP3326-100 µg, ATGP3326-250 µg, ATGP3326-500 µg, ATGP3326-1 mg, ATGP3326-10, ATGP3326-20, ATGP3326-50, ATGP3326-100, ATGP3326-250, ATGP3326-500, ATGP3326-1

References & Citations

Zola H., et al. (2007) J Immunol Methods. 318:1-5.; ; Cottin V., et al. (2002) J Immunol. 168:4095-4102.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Apoptosis

NCBI Accession Number

NP_001056

Uniprot Accession Number

P19438

Species

Human

N Terminal Sequence

Ala

AA Sequence

ADPLVPHLGD REKRDSVCPQ GKYIHPQNNS ICCTKCHKGT YLYNDCPGPG QDTDCRECES GSFTASENHL RHCLSCSKCR KEMGQVEISS CTVDRDTVCG CRKNQYRHYW SENLFQCFNC SLCLNGTVHL SCQEKQNTVC TCHAGFFLRE NECVSCSNCK KSLECTKLCL PQIENVKGTE DSGTTLEPKS CDKTHTCPPC PAPELLGGPS VFLFPPKPKD TLMISRTPEV TCVVVDVSHE DPEVKFNWYV DGVEVHNAKT KPREEQYNST YRVVSVLTVL HQDWLNGKEY KCKVSNKALP APIEKTISKA KGQPREPQVY TLPPSRDELT KNQVSLTCLV KGFYPSDIAV EWESNGQPEN NYKTTPPVLD SDGSFFLYSK LTVDKSRWQQ GNVFSCSVMH EALHNHYTQK SLSLSPGKHH HHHH