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Recombinant mouse Cathepsin L protein

CTSL, also known as cathepsin L1, is a lysosomal cysteine protease expressed in most eukaryotic cells. It plays a major role in intracellular protein catabolism and is potent in degrading collagen, laminin, elastin, as well as alpha-1 protease inhibitor and other structural proteins of basement membranes. Recombinant mouse CTSL, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Procathepsin L, Cathepsin L1, Major excreted protein, MEP, CTSL, CTSL1, p39 cysteine proteinase

Expression System

Baculovirus

Antigen Species

Mouse

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

36.8 kDa (325aa)

Additionnal Information

Cathepsin L, Cathepsin L1, CTSL, 1190035F06Rik, CatL, Ctsl1, fs, MEP, nkt, ATGP3318-10 µg, ATGP3318-20 µg, ATGP3318-50 µg, ATGP3318-100 µg, ATGP3318-250 µg, ATGP3318-500 µg, ATGP3318-1 mg, ATGP3318-10, ATGP3318-20, ATGP3318-50, ATGP3318-100, ATGP3318-250, ATGP3318-500, ATGP3318-1

References & Citations

Goretzki L., et al. (1992) FEBS Lett. 297:112-118.; ; Taggart CC., et al. (2001) J Biol Chem. 276:33345-33352.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Neuroscience

NCBI Accession Number

NP_034114

Uniprot Accession Number

P06797

Species

Mouse

N Terminal Sequence

Thr18

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