Recombinant mouse Cathepsin L protein
CTSL, also known as cathepsin L1, is a lysosomal cysteine protease expressed in most eukaryotic cells. It plays a major role in intracellular protein catabolism and is potent in degrading collagen, laminin, elastin, as well as alpha-1 protease inhibitor and other structural proteins of basement membranes. Recombinant mouse CTSL, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Procathepsin L, Cathepsin L1, Major excreted protein, MEP, CTSL, CTSL1, p39 cysteine proteinase
Expression System
Baculovirus
Antigen Species
Mouse
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 90% by SDS-PAGE
Molecular Weight
36.8 kDa (325aa)
Additionnal Information
References & Citations
Goretzki L., et al. (1992) FEBS Lett. 297:112-118.; ; Taggart CC., et al. (2001) J Biol Chem. 276:33345-33352.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Neuroscience
NCBI Accession Number
NP_034114
Uniprot Accession Number
P06797
Species
Mouse
N Terminal Sequence
Thr18
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