Recombinant human S100B protein
S100B also known as protein S100-B. S100B is a protein of the S100 protein family. S100 proteins comprise a multigene family of EF-hand calcium binding proteins that engage in multiple functions in response to cellular stress. S100B protein has been implicated in oligodendrocyte progenitor cell (OPC) regeneration in response to demyelinating insult. Also, S100B and other members of S100 proteins are specifically interact with PP5-TPR and inhibited the PP5-Hsp90 interaction. Recombinant Human S100B was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Expression System
E.coli
Antigen Species
Human
Tag
Non-Tagged
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 95% by SDS-PAGE
Molecular Weight
10.7 kDa (92aa)
Additionnal Information
References & Citations
Gilquin B., et al. (2010) Mol Cell Biol. 30 (11) : 2724-36.; ; Yamaguchi F., et al. (2012) J Biol Chem. 287 (17) : 13787-98.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Cell Cycle
NCBI Accession Number
NP_006263.1
Uniprot Accession Number
P04271
Species
Human
AA Sequence
MSELEKAMVA LIDVFHQYSG REGDKHKLKK SELKELINNE LSHFLEEIKE QEVVDKVMET LDNDGDGECD FQEFMAFVAM VTTACHEFFE HE
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