Recombinant human S100B protein

S100B also known as protein S100-B. S100B is a protein of the S100 protein family. S100 proteins comprise a multigene family of EF-hand calcium binding proteins that engage in multiple functions in response to cellular stress. S100B protein has been implicated in oligodendrocyte progenitor cell (OPC) regeneration in response to demyelinating insult. Also, S100B and other members of S100 proteins are specifically interact with PP5-TPR and inhibited the PP5-Hsp90 interaction. Recombinant Human S100B was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

S100 calcium binding protein B, S100 calcium binding protein beta neural, S100beta, S100 protein beta chain, S100 protein subunit beta, S100 calcium-binding protein B

Expression System

E.coli

Antigen Species

Human

Tag

Non-Tagged

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 95% by SDS-PAGE

Molecular Weight

10.7 kDa (92aa)

Additionnal Information

S-100beta, S100beta, S-100B, S100B, S-100 protein subunit beta, S100 protein subunit beta, S-100 protein beta subunit, S-100 protein beta chain, S100 protein beta chain, S-100 calcium-binding protein B, S100 calcium-binding protein B, S-100 calcium binding protein beta neural, S100 calcium binding protein beta neural, S-100 calcium binding protein beta chain, S100 calcium binding protein beta chain, S-100 calcium binding protein beta, S100 calcium binding protein beta, S-100 calcium binding protein B, S100 calcium binding protein B, S-100 beta, S100 beta, S-100, S100, S 100 protein beta subunit, S 100 protein beta chain, Protein S-100-B, Protein S100-B, Protein S-100 B, Protein S100 B, NEF, ATGP3314-10 µg, ATGP3314-20 µg, ATGP3314-50 µg, ATGP3314-100 µg, ATGP3314-250 µg, ATGP3314-500 µg, ATGP3314-1 mg, ATGP3314-010, ATGP3314-020, ATGP3314-050, ATGP3314-100, ATGP3314-250, ATGP3314-500, ATGP3314-01M

References & Citations

Gilquin B., et al. (2010) Mol Cell Biol. 30 (11) : 2724-36.; ; Yamaguchi F., et al. (2012) J Biol Chem. 287 (17) : 13787-98.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Cell Cycle

NCBI Accession Number

NP_006263.1

Uniprot Accession Number

P04271

Species

Human

AA Sequence

MSELEKAMVA LIDVFHQYSG REGDKHKLKK SELKELINNE LSHFLEEIKE QEVVDKVMET LDNDGDGECD FQEFMAFVAM VTTACHEFFE HE

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