Recombinant human LIFR alpha/LIFR protein
LIFR, also known as leukemia inhibitory factor receptor, is the receptor for leukemia inhibitory factor, a pleiotropic cytokine affecting the differentiation, survival, and proliferation of a wide variety of cells in the adult and the embryo. LIFR plays an important role in several aspects of early pregnancy such as blastocyst implantation in the uterus. Recombinant human LIFR, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Leukemia inhibitory factor receptor, LIFR, CD118, LIF-R, SJS2, STWS, SWS, LIF receptor subunit alpha
Expression System
Baculovirus
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 90% by SDS-PAGE
Molecular Weight
90.5 kDa (798aa)
Additionnal Information
References & Citations
Gearing DP., et al. (1991) EMBO J. 10:2839-2848.; ; Cheng JG., et al. (2001) Proc Nati Acad Sci USA 98:8680-8685.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Immunology
NCBI Accession Number
NP_002301.1
Uniprot Accession Number
P42702
Species
Human
N Terminal Sequence
Ala
AA Sequence
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