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Recombinant human LIFR alpha/LIFR protein

LIFR, also known as leukemia inhibitory factor receptor, is the receptor for leukemia inhibitory factor, a pleiotropic cytokine affecting the differentiation, survival, and proliferation of a wide variety of cells in the adult and the embryo. LIFR plays an important role in several aspects of early pregnancy such as blastocyst implantation in the uterus. Recombinant human LIFR, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Leukemia inhibitory factor receptor, LIFR, CD118, LIF-R, SJS2, STWS, SWS, LIF receptor subunit alpha

Expression System

Baculovirus

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

90.5 kDa (798aa)

Additionnal Information

LIF R a, Leukemia inhibitory factor receptor, LIFR, CD118, LIF-R, SJS2, STWS, SWS, ATGP3310-10 µg, ATGP3310-20 µg, ATGP3310-50 µg, ATGP3310-100 µg, ATGP3310-250 µg, ATGP3310-500 µg, ATGP3310-1 mg, ATGP3310-10, ATGP3310-20, ATGP3310-50, ATGP3310-100, ATGP3310-250, ATGP3310-500, ATGP3310-1

References & Citations

Gearing DP., et al. (1991) EMBO J. 10:2839-2848.; ; Cheng JG., et al. (2001) Proc Nati Acad Sci USA 98:8680-8685.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Immunology

NCBI Accession Number

NP_002301.1

Uniprot Accession Number

P42702

Species

Human

N Terminal Sequence

Ala

AA Sequence

QKKGAPH DLKCVTNNLQ VWNCSWKAPS GTGRGTDYEV CIENRSRSCY QLEKTSIKIP ALSHGDYEIT INSLHDFGSS TSKFTLNEQN VSLIPDTPEI LNLSADFSTS TLYLKWNDRG SVFPHRSNVI WEIKVLRKES MELVKLVTHN TTLNGKDTLH HWSWASDMPL ECAIHFVEIR CYIDNLHFSG LEEWSDWSPV KNISWIPDSQ TKVFPQDKVI LVGSDITFCC VSQEKVLSAL IGHTNCPLIH LDGENVAIKI RNISVSASSG TNVVFTTEDN IFGTVIFAGY PPDTPQQLNC ETHDLKEIIC SWNPGRVTAL VGPRATSYTL VESFSGKYVR LKRAEAPTNE SYQLLFQMLP NQEIYNFTLN AHNPLGRSQS TILVNITEKV YPHTPTSFKV KDINSTAVKL SWHLPGNFAK INFLCEIEIK KSNSVQEQRN VTIKGVENSS YLVALDKLNP YTLYTFRIRC STETFWKWSK WSNKKQHLTT EASPSKGPDT WREWSSDGKN LIIYWKPLPI NEANGKILSY NVSCSSDEET QSLSEIPDPQ HKAEIRLDKN DYIISVVAKN SVGSSPPSKI ASMEIPNDDL KIEQVVGMGK GILLTWHYDP NMTCDYVIKW CNSSRSEPCL MDWRKVPSNS TETVIESDEF RPGIRYNFFL YGCRNQGYQL LRSMIGYIEE LAPIVAPNFT VEDTSADSIL VKWEDIPVEE LRGFLRGYLF YFGKGERDTS KMRVLESGRS DIKVKNITDI SQKTLRIADL QGKTSYHLVL RAYTDGGVGP EKSMYVVTKE NS

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