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Recombinant human VEGF-C protein

VEGFC, also known as vascular endothelial growth factor C, is a member of the VEGF family. This growth factors play key roles in the physiology and pathology of many aspects of the cardiovascular system including hematopoiesis, angiogenesis and vascular permeability. Traces of VEGFC are also detected in brain, liver, thymus, skeletal muscles, spleen, prostate, testis and colon. Unlike other VEGF family members, VEGFC expression is not regulated by hypoxia. Recombinant human VEGFC, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Vascular endothelial growth factor C, Flt4-L, LMPH1D, VRP

Expression System

Baculovirus

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

14.2 kDa (125aa)

Additionnal Information

VEGF-C, Vascular endothelial growth factor C, Flt4-L, LMPH1D, VRP, ATGP3309-10 µg, ATGP3309-20 µg, ATGP3309-50 µg, ATGP3309-100 µg, ATGP3309-250 µg, ATGP3309-500 µg, ATGP3309-1 mg, ATGP3309-10, ATGP3309-20, ATGP3309-50, ATGP3309-100, ATGP3309-250, ATGP3309-500, ATGP3309-1

References & Citations

Hatano Y., et al. (2014) Biochem. Biophys. Res. Commun. 446:149-154.; ; Ciobanu M., et al. (2013) Rom J Morphol. Embryol. 54:925-934.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 20% glycerol

Scientific Category

Cardiovascular

NCBI Accession Number

NP_005420

Uniprot Accession Number

P49767

Species

Human

N Terminal Sequence

Ala

AA Sequence

ADPAHYNTEI LKSIDNEWRK TQCMPREVCI DVGKEFGVAT NTFFKPPCVS VYRCGGCCNS EGLQCMNTST SYLSKTLFEI TVPLSQGPKP VTISFANHTS CRCMSKLDVY RQVHSIIRRH HHHHH

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