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Recombinant human CDCP1 protein

CDCP1, also known as CUB domain-containing protein 1 isoform 1, is a transmembrane protein containing three extracellular CUB domains. This protein is involved in cell adhesion and cell matrix association. Also, CDCP1 may play a role in the regulation of anchorage versus migration or proliferation versus differentiation via its phosphorylation and may be a novel marker for leukemia diagnosis and for immature hematopoietic stem cell subsets. The extracellular region of human CDCP1 shares amino acid identity sequence with that of the mouse protein. Recombinant human CDCP1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

CDCP1, CD318, SIMA135, TRASK, Membrane glycoprotein gp140

Expression System

Baculovirus

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

72.8 kDa (646aa)

Additionnal Information

CDCP1, CDCP1, CD318, SIMA135, TRASK, Membrane glycoprotein gp140, ATGP3306-10 µg, ATGP3306-20 µg, ATGP3306-50 µg, ATGP3306-100 µg, ATGP3306-250 µg, ATGP3306-500 µg, ATGP3306-1 mg, ATGP3306-10, ATGP3306-20, ATGP3306-50, ATGP3306-100, ATGP3306-250, ATGP3306-500, ATGP3306-1

References & Citations

Miura S., et al. (2014) Exp. Cell Res. 321:209-218.; ; Uekita., et al. (2013) Cancer Sci. 104:865-870.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Cancer

NCBI Accession Number

NP_073753.3

Uniprot Accession Number

Q9H5V8

Species

Human

N Terminal Sequence

Phe30

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