What is the catalog number for Recombinant human 4-1BB/CD137/TNFRSF9 protein?

The catalog number for Recombinant human 4-1BB/CD137/TNFRSF9 protein is ATGP3303-050.

What sizes are available for Recombinant human 4-1BB/CD137/TNFRSF9 protein?

Recombinant human 4-1BB/CD137/TNFRSF9 protein is available in the following size(s): 50 µg.

Is Recombinant human 4-1BB/CD137/TNFRSF9 protein in stock?

Recombinant human 4-1BB/CD137/TNFRSF9 protein is currently made to order / not held in immediate stock. Contact us for lead time.

Recombinant human 4-1BB/CD137/TNFRSF9 protein

TNFRSF9, also known as tumor necrosis factor receptor superfamily member 9, is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. Recombinant human TNFRSF9, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Specifications

Human TNFSF9 (CAT# ATGP0308) is coated at 2 µg/mL (100 ul/well) can bind Human TNFRSF9. The ED50 range ≤ 50 ng/mL.

Product Name Alternative

Tumor necrosis factor receptor superfamily member 9, 4-1BB ligand receptor, CDw137, T-cell antigen 4-1BB homolog, T-cell antigen ILA, CD137

Expression System

Baculovirus

Antigen Species

Human

Tag

HIgG-His-Tag

Applications

SDS-PAGE, Bioactivity

Concentration

0.5 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Bioactivity

Measured by its binding ability in a functional ELISA with Human TNFSF9 (CAT# ATGP0308) . The ED50 range ≤ 50 ng/mL.

Molecular Weight

45.3 kDa (411aa)

Additionnal Information

41BB, TNFRSF9, TNFRSF9, Ly63, 4-1BB, ILA, CD137, CDw137, ATGP3303-10 µg, ATGP3303-20 µg, ATGP3303-50 µg, ATGP3303-100 µg, ATGP3303-250 µg, ATGP3303-500 µg, ATGP3303-1 mg, ATGP3303-10, ATGP3303-20, ATGP3303-50, ATGP3303-100, ATGP3303-250, ATGP3303-500, ATGP3303-1

References & Citations

Litjens NH., et al. (2013) Clin. Exp. Immunol. 174:179-191.; ; Lee SJ., et al. (2013) Eur. J. Immunol. 43:1839-1848.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Immunology

NCBI Accession Number

NP_001552

Uniprot Accession Number

Q07011

Species

Human

N Terminal Sequence

Ala

AA Sequence

FERTRSL QDPCSNCPAG TFCDNNRNQI CSPCPPNSFS SAGGQRTCDI CRQCKGVFRT RKECSSTSNA ECDCTPGFHC LGAGCSMCEQ DCKQGQELTK KGCKDCCFGT FNDQKRGICR PWTNCSLDGK SVLVNGTKER DVVCGPSPAD LSPGASSVTP PAPAREPGHS PQ