Recombinant human CD208/LAMP3 protein
LAMP3, also known as lysosome-associated membrane glycoprotein 3, is a member of the lysosome-associated membrane protein family. LAMP3 and CD68 share very similar predicted structure. It may play a role in dendritic cell function and in adaptive immunity. Overexpression of LAMP3 is actively involved in tumor invasion through increased migration into lymph-vascular spaces. Recombinant human LAMP3, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
CD208, DC-LAMP, DC-lysosome-associated membrane glycoprotein, LAMP, LAMP-3, Lysosome-associated membrane glycoprotein 3, TSC403
Expression System
Baculovirus
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 90% by SDS-PAGE
Molecular Weight
38.8 kDa (362aa)
Additionnal Information
References & Citations
Salaun B., et al. (2004) Am J Pathol. 164:861-871.; ; Kanao H., et al. (2005) Cancer Res. 65:8640-8645.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Immunology
NCBI Accession Number
NP_055213.2
Uniprot Accession Number
Q9UQV4
Species
Human
N Terminal Sequence
Lys28
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