Recombinant human CD69 protein

CD69, also known as early activation antigen CD69, is a type 2 transmembrane glycoprotein in the C-type lectin family. Also, CD69 is a very early activation Ag of T lymphocytes. It is involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets. This protein plays a role in the pathogenesis of allergen induced eosinophilic airway inflammation and responsiveness. Recombinant human CD69, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Early activation antigen CD69, Activation inducer molecule, AIM, BL-AC/P26, C-type lectin domain family 2 member C, EA1, Early T-cell activation antigen p60, GP32/28, Leukocyte surface antigen Leu-23, MLR-3, CLEC2C

Expression System

Baculovirus

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by absorbance at 280 nm)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 95% by SDS-PAGE

Molecular Weight

17 kDa (147aa)

Additionnal Information

CD69, CD69, AIM, BL-AC/P26, CLEC2C, EA1, GP32/28, MLR-3, ATGP3298-10 µg, ATGP3298-20 µg, ATGP3298-50 µg, ATGP3298-100 µg, ATGP3298-250 µg, ATGP3298-500 µg, ATGP3298-1 mg, ATGP3298-10, ATGP3298-20, ATGP3298-50, ATGP3298-100, ATGP3298-250, ATGP3298-500, ATGP3298-1

References & Citations

Li J., et al. (2013) Cell. Immunol. 285:23-30.; ; Gonzalez-Amaro R., et al. (2013) Trends Mol. Med. 19 (10) :625-632.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Immunology

NCBI Accession Number

NP_001772

Uniprot Accession Number

Q07108

Species

Human

N Terminal Sequence

Ala

AA Sequence

ADPSVGQYNC PGQYTFSMPS DSHVSSCSED WVGYQRKCYF ISTVKRSWTS AQNACSEHGA TLAVIDSEKD MNFLKRYAGR EEHWVGLKKE PGHPWKWSNG KEFNNWFNVT GSDKCVFLKN TEVSSMECEK NLYWICNKPY KHHHHHH