Recombinant human Chitinase 3-like 2/CHI3L2 protein
CHI3L2, also known as chitinase-3-like protein 2, belongs to chitinase protein family. It is secreted by synovial fibroblasts, chondrocytes, and TGFb/IL4 stimulated monocyte derived macrophages. It has been proposed as a potential biomarker for osteoarthritis. Recombinant human CHI3L2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
CHI3L2, CHIL2, YKL-39, YKL39
Expression System
Baculovirus
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 90% by SDS-PAGE
Molecular Weight
41.9 kDa (372aa)
Additionnal Information
References & Citations
Hu B., et al. (1996) J. Biol. Chem. 271:19415-19420.; ; Gratchev A., et al. (2008) Biomarker Insights. 3:39-44.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Stem cell
NCBI Accession Number
NP_003991
Uniprot Accession Number
Q15782
Species
Human
N Terminal Sequence
Tyr27
AA Sequence
Frequently Asked Questions
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