Recombinant human ASPA protein
ASPA also known as aspartoacylase, is expressed in liver, lung and kidney tissue, as well as in skeletal muscle and in cerebral white matter. Existing as a homodimer, ASPA functions to catalyze the deacetylation of N-acetylaspartic acid (NAA) (a protein whose hydrolysis is crucial to maintenance of intact white matter) to produce acetate and L-aspartate. Recombinant human ASPA, was expressed in E. coli and purified by conventional chromatography techniques.
Product Specifications
Product Name Alternative
ACY2, ASP
Expression System
E.coli
Antigen Species
Human
Tag
Non-Tagged
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
35.7 kDa (313aa)
Additionnal Information
References & Citations
Le Coq., et al. (2006) Biochemistry 45: 5878-5884.; ; Le Coq., et al. (2008) Biochemistry 47: 3484-3492.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Neuroscience
NCBI Accession Number
NP_000040
Uniprot Accession Number
P45381
Species
Human
AA Sequence
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