Recombinant human ZAG protein
AZGP1, also known as zinc-alpha-2-glycoprotein, is a member of the MHC class 1 family of proteins. It is reported to associate with PIP (prolactin-inducible protein) but not the MHC light chain, B 2-microglobulin. It is produced by secretory epithelia and is present in most body fluids. It stimulates lipid degradation in adipocytes and causes the extensive fat losses associated with some advanced cancers. Recombinant human AZGP1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
AZGP1, ZA2G, ZAG
Expression System
Baculovirus
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 95% by SDS-PAGE
Molecular Weight
33.2 kDa (286aa)
Additionnal Information
References & Citations
Freije J. P., et al. (1993) Genomics 18:575-587.; ; Massan M. I., et al. (2008) J. Mol. Biol. 384:663-672.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Hormones & Cytokines
NCBI Accession Number
NP_001176
Uniprot Accession Number
P25311
Species
Human
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