Recombinant mouse IL-17A protein
IL17A, also known as Interleukin-17A, plays an important role in anti-microbial and chronic inflammation. Mature human IL17A shares 60% amino acid sequence identity with mouse and rat IL17A. It promotes protective mucosal and epidermal inflammation in response to microbial infection and induces chemokine production, neutrophil influx, and the production of antibacterial peptides. Recombinant mouse IL17A, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Interleukin 17A, Cytotoxic T-lymphocyte-associated antigen 8, CTLA-8, Ctla-8, Il17, IL-17A
Expression System
Baculovirus
Antigen Species
Mouse
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 95% by SDS-PAGE
Molecular Weight
16kDa (141aa)
Additionnal Information
References & Citations
Yao Z., et al. (1995) J. Immunol. 155:5483-5436.; ; Kennedy J., et al. (1996) J. Interferon Cytokine Res. 16:611-617.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Immunology
NCBI Accession Number
NP_034682.1
Uniprot Accession Number
Q62386
Species
Mouse
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