Recombinant mouse Cathepsin E protein
CTSE, also known as cathepsin E, belongs to an intracellular aspartic protease of the pepsin family. It plays an important role in the degradation of proteins, the generation of bioactive proteins, and antigen processing. It is efficient in cleaving the Swedish mutant of amyloid precursor protein (APP) at the B site but show almost on reactivity with the wild-type APP. Recombinant mouse CTSE, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
CTSE, A430072003Rik, C920004C08Rik, CatE, CE
Expression System
Baculovirus
Antigen Species
Mouse
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 95% by SDS-PAGE
Molecular Weight
41.8 kDa (385aa)
Additionnal Information
References & Citations
Tsukuba T., et al. (2000) Mol. Cells 10:601-611.; ; Bennett K., et al. (1992) Eur. J. Immunol. 22: 1519-1524.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Immunology
NCBI Accession Number
NP_031825
Uniprot Accession Number
P70269
Species
Mouse
AA Sequence
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